Table 3. Summary of overall analysis and sensitivity analysis.
| Variables | Number of studies | Sensitivity (95% CI) | Specificity (95% CI) | DOR(95%CI) | PLR (95%CI) | NLR (95%CI) | AUC(95%CI) | Q-value |
|---|---|---|---|---|---|---|---|---|
| Overall analysis | 18 | 0.91(0.87–0.94) | 0.96(0.95–0.96) | 163.03(54.62–486.63) | 14.42(7.92–26.26) | 0.1(0.05–0.2) | 0.97 | 0.92 |
| Cut-off of presenting nuclear staining | 13 | 0.94(0.89–0.97) | 0.94(0.91–0.95) | 135.91(57.19–322.99) | 13.41(7.58–23.72) | 0.12(0.07–0.19) | 0.97 | 0.92 |
| Pleural effusion samples | 7 | 0.84(0.76–0.91) | 0.96(0.95–0.97) | 91.84(12.42–679.04) | 11.15(3.05–40.73) | 0.12(0.03–0.47) | 0.95 | 0.89 |
DOR, diagnostic OR; PLR, positive likelihood ratio; NLR, negative likelihood ratio; AUC, area under the receiver operating characteristic curve.