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. 2015 Mar 30;5:9301. doi: 10.1038/srep09301

Table 1. Fourteen proteins were significantly enriched within the GSH metabolism pathway.

Uniprot accession no. Gene IDs Gene symbol Protein description CoverageA 127/126B
P15144 290 ANPEP Aminopeptidase 3.62 1.257
Q9Y2Q3-3 373156 GSTK1 Glutathione S-transferase kappa 1 15.89 0.885
P11413 2539 G6PD Glucose-6-phosphate 1-dehydrogenase 31.46 0.498
P21266 2947 GSTM3 Glutathione S-transferase Mu 3 51.56 0.723
P78417 9446 GSTO1 Glutathione S-transferase omega-1 36.10 1.268
P00390-5 2936 GSR Glutathione reductase 8.18 0.851
O75223 79017 GGCT Gamma-glutamylcyclotransferase 21.28 0.631
P48637 2937 GSS Glutathione synthetase 5.27 0.932
O75874 3417 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 28.50 0.568
P48735 3418 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 40.49 0.643
P28838-2 51056 LAP3 Cytosol aminopeptidase 33.20 0.777
P09211 2950 GSTP1 Glutathione S-transferase P 52.86 1.612
P10620-2 4257 MGST1 microsomal glutathione S-transferase 1 28.74 0.932
P52209 5226 PGD 6-phosphogluconate dehydrogenase 28.99 0.703

AData associated with the particular peptide from our proteomics analysis were matched to the peptide database.

BMCF-7 peptide samples of were labeled with TMT2-126 isobaric tags; MCF-7/ADR peptide samples of were labeled with TMT2-127 isobaric tags. The values of 127/126 represent the relative quantitation ratio of the DEPs in two cells.