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(A) Autoradiographic short-axis images of 18F-FBzBMS in healthy rat hearts with and without ETA antagonist BMS-207940 pretreatment. (B) Effects of medication on cardiac 18F-FBzBMS uptake. Dose dependent blockage by bosentan was shown. *P < 0.001 vs. control. mg/kgw = mg per kg of body weight 91.
