Table 3.
Some of Radiolabeled Apoptosis Imaging Agents in Preclinical and Clinical Trials.
| Radiotracers | Class | Status | Investigators | Disease Group | Ref. |
|---|---|---|---|---|---|
| 99mTc-HYNIC-Annexin V | Protein | Phase II/III | Theseus Imaging Corp. | NSCLC | 75, 76 |
| 99mTc-BTAP-Annexin V | Protein | Phase I | Theseus Imaging Corp. | Healthy Volunteers | 67 |
| 18F-CP18 | Peptide | Phase II | Kurdziel et al. | Ovarian Neoplasms, Fallopian Tube Neoplasms |
99 |
| 18F-ICMT-11 | Isatin family | Phase I | QuIC-ConCePT Consortium | Healthy Volunteers | 133 |
| 18F-ML-10 | Aposense family | Phase I/II | NST NeuroSurvival Technologies Ltd. | Acute Ischemic Cerebral Stroke, Metastatic Brain Tumors |
114, 215 |