Table 4.
MSI status of individual loci for Series 2 (no normal tissue control). An unstable locus is defined by a cut-off of ≥2 base pair deviations from the normal tissue for mononucleotide markers. All MSI-H (high metastasis) tumours demonstrated instability in both BAT25 and BAT26 MSI loci. Abbreviations: M, mononucleotide; +, unstable locus; −, stable locus.
| Cases | BAT25 (M) (NGS/Multiplex PCR) | BAT26 (M) (NGS/Multiplex PCR ) | MSI status (NGS) | MSI status (Multiplex PCR) |
|---|---|---|---|---|
| 1 | +/+ | +/+ | High | High |
| 2 | +/+ | +/+ | High | High |
| 3 | −/− | −/− | Stable | Stable |
| 4 | +/+ | +/+ | High | High |
| 5 | −/− | −/− | Stable | Low |
| 6 | −/− | −/− | Stable | Stable |