Table 2.
Gene ontology enrichment analysis on the transcriptomes of FW vs SW 1 h in medaka intestine (p < 0.05)
| Biological process | Molecular function | Cellular component | ||||
|---|---|---|---|---|---|---|
| Rank | Annotation | p-value | Annotation | p-value | Annotation | p-value |
| 1 | protein phosphorylation | 1.90E-10 | protein binding | 8.60E-13 | integrin complex | 1.60E-03 |
| 2 | regulation of transcription, DNA-dependent | 1.10E-08 | protein tyrosine kinase activity | 8.10E-08 | extra cellular region | 7.50E-03 |
| 3 | cell adhesion | 4.20E-05 | protein serine/threonine kinase activity | 1.70E-05 | Cytoskeleton | 8.60E-03 |
| 4 | regulation of small GTPase mediated signal transduction | 2.20E-04 | actin binding | 4.20E-05 | proteinaceous extracellur matri | 2.30E-02 |
| 5 | signal transduction | 2.20E-04 | sequence-specific DNA binding transcripttion factor activity | 5.30E-05 | ||
| 6 | integrin-mediated signaling pathway | 1.01E-03 | guanyl-nucleotide exchange factor activity | 5.70E-04 | ||
| 7 | intracellular signal transduction | 1.72E-03 | phospholipid binding | 1.35E-03 | ||
| 8 | glucose metabolic process | 1.94E-03 | sequence-specific DNA binding | 2.12E-03 | ||
| 9 | cytokine-mediated signaling pathway | 2.27E-03 | non-membrane spanning protein tyrosine kinase activity | 2.69E-03 | ||
| 10 | peptidy I-tyrosine dephosphorylation | 2.43E-03 | cytokine receptor activity | 2.69E-03 | ||
| 11 | cell cycle arrest | 4.30E-03 | ATP binding | 3.86E-03 | ||
| 12 | multicellular organismal development | 5.18E-03 | G-protein coupled peptide receptor activity | 3.90E-03 | ||
| 13 | G-protein coupled receptor signaling pathway | 5.90E-03 | protein domain specific binding | 4.53E-03 | ||
| 14 | neurotransmitter transport | 9.35E-03 | MAP kinase activity | 5.07E-03 | ||
| 15 | intracellular protein kinase cascade | 1.75E-02 | protien tyrosine/serine/threonine phosphatase activity | 5.98E-03 | ||
| 16 | MAPK cascade | 1.79E-02 | receptor activity | 6.97E-03 | ||
| 17 | transmembrane receptor protein tyrosine kinase signaling pat… | 1.93E-02 | calcium ion binding | 7.11E-03 | ||
| 18 | positive regulation of GTPase activity | 2.71E-02 | protein tyrosine phosphatase activity | 1.02E-02 | ||
| 19 | regulation of cellular component biogenesis | 2.71E-02 | transmembrane receptor protein tyrosine kinase activity | 1.62E-02 | ||
| 20 | hormophilic cell adhesion | 3.446E-02 | GTPase activator activity | 1.76E-02 | ||
| 21 | regulation of ARF protein signal transduction | 3.48E-10 | neurotransmitter: sodium symporter activity | 2.08E-02 | ||
| 22 | regulation of cellular component organization | 3.48E-02 | small GTPase regulator activity | 2.20E-02 | ||
| 23 | cell-matrix adhesion | 4.77E-02 | calmodulin binding | 2.65E-03 | ||
| 24 | polyol metabolic process | 4.88E-02 | organic acid transmembrane transporter activity | 2.89E-02 | ||
| 25 | ubiquitin protein ligase activity | 2.99E-02 | ||||
| 26 | protein complex binding | 3.27E-02 | ||||
| 27 | phosphotransferase activity, alcohol group as acceptor | 3.67E-02 | ||||
| 28 | ARF guanyl-nucleotide exchange factor activity | 3.92E-02 | ||||
| 29 | signal transducer activity | 4.66E-02 | ||||
| 30 | kinase activity | 4.79E-02 |