Table 2.

Myroilysin specificity for recombinant human tropoelastin ^a.

	P4	P3	P2	P1	P1′	P2′	P3′	P4′	Occurrence Number
G	28.89	22.22	35.56	36.67	36.67	16.67	31.11	22.22	207
V	14.44	13.33	3.33	7.78	12.22	16.67	8.89	22.22	89
P	14.44	31.11	8.89	11.11	3.33	27.78	15.56	20.00	119
A	20.00	14.44	17.78	21.11	22.22	17.78	17.78	14.44	131
L	5.56	6.67	10.00	6.67	11.11	8.89	6.67	6.67	56
Y	3.33	0.00	7.78	2.22	1.11	1.11	3.33	0.00	17
F	3.33	2.22	5.56	4.44	1.11	0.00	1.11	1.11	17
I	1.11	1.11	3.33	0.00	5.56	3.33	1.11	2.22	16
C	0.00	0.00	0.00	0.00	1.11	1.11	1.11	1.11	4
K	3.33	5.56	3.33	7.78	3.33	3.33	7.78	5.56	36
Q	1.11	1.11	2.22	0.00	0.00	0.00	1.11	1.11	6
T	1.11	1.11	0.00	1.11	2.22	0.00	0.00	1.11	6
R	1.11	0.00	0.00	1.11	0.00	1.11	2.22	1.11	6
S	2.22	0.00	1.11	0.00	0.00	2.22	2.22	1.11	8
E	0.00	1.11	1.11	0.00	0.00	0.00	0.00	0.00	2

^a Occurrence of different amino acids at the substrate positions P1–P4 and P1′–P4′, which refers to the preference for a particular amino acid at a given position. The last column shows the number of occurrences of each amino acid.