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. 2015 Mar 30;19(1):156. doi: 10.1186/s13054-015-0862-4

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© Das; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Metabolism of essential fatty acids and their role in inflammation and its resolution. AA, arachidonic acid; A-FABP, adipose-fatty acid binding protein; ALA, alpha-linolenic acid; DGLA, dihomo-gamma-linolenic acid; DHA, docosahexaenoic acid; eNO, endothelial nitric oxide; EPA, eicosapentaenoic acid; GLA, gamma-linolenic acid; HMGB1, high-mobility group box 1; IL, interleukin; LA, linolenic acid; LT, leukotriene; PG, prostaglandin; PlGF, placental growth factor; PGI, prostacyclin; PUFA, polyunsaturated fatty acid; ROS, reactive oxygen species; sFlt1, Soluble fms-like tyrosine kinase 1; TNFα, tumor necrosis factor alpha; TX, thromboxane; VEGF, vascular endothelial growth factor.