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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Magn Reson Med. 2014 Mar 6;73(2):614–622. doi: 10.1002/mrm.25174

Figure 3.

Figure 3

A schematic drawing of the pulse sequence used for continuous IHMT imaging. A nonselective saturation 2 seconds before imaging is followed by a continuous off-resonance RF irradiation applied for up to 1020ms. The RF power is ramped up and down over 10ms at the beginning and end of the irradiation to minimize broadband transients. Dual frequency irradiation is achieved with sinusoidal modulation of the RF envelope. Image acquisition with a single shot RARE sequence is performed after a brief 15 ms wait to allow for gradient crushing and decay of any transients. Acquisition of images with dual frequency MT irradiation is interleaved with acquisition of single frequency MT images.