Table 1.
PBNT embryo development after VPA treatment
| Treatment | No.embryos cultured | Cleavage (%) | 8-16 cells (%) | Morula (%) | Blastocysts (%) | |
|---|---|---|---|---|---|---|
| VPA at different concentrations (mM) | Control | 136 | 98(72.1)a | 69(50.7)a | 2(1.5) | 2(1.5) |
| 0.5 | 153 | 120(78.4)a | 95(61.9)a | 2(1.3) | 1(0.7) | |
| 1.0 | 147 | 104(70.7)a | 75(51.0)a | 1(0.7) | 1(0.7) | |
| 2.0 | 138 | 81 (58.7)b | 29(21.0)b | 1(0.7) | 0(0.0) | |
| 4.0 | 158 | 79(50.0)b | 12(7.6)b | 0(0.0) | 0(0.0) | |
| VPA at 0.5 mM for differenttimes (h) | Control | 118 | 83(70.3)a | 52(44.1)b | 1(0.8) | 1(0.8) |
| 5 | 142 | 99 (69.7)a | 60(42.3)b | 1(0.7) | 1(0.7) | |
| 12 | 151 | 107(70.9)a | 71(47.0)b | 1(0.7) | 1(0.7) | |
| 24 | 146 | 111(76.0)a | 95(65.1)a | 1(0.7) | 1(0.7) | |
| 48 | 149 | 102(68.5)a | 74(49.7)b | 0(0.0) | 0(0.0) |
In the column, the same letter in superscript denotes no significant difference, different letter in superscript denotes significant difference. p<0.05.