Figure 4.

Correlation of CpG _O/E with transcript abundance. Mean gene expression values were generated from 25 equally sized quantiles based on CpG_O/E. Each gene was assigned an expression value equal to its average expression across all samples. Each data point represents mean of the expression values for all genes included in the quantile plotted against mean CpG_O/E for the quantile; the whiskers denote standard errors. Green and red arrows indicate the means for the two mixture component shown in Figure 1A. The black arrow indicates the point of separation between the components.