Fig. 6.

Forest plot shows a comparative analysis of the occurrence of cardiovascular events in atrial fibrillation patients, whether taking or not taking anticoagulants, when evaluated by means of the CHA₂DS₂-VASc score. P ≥0.05 was considered statistically significant. The occurrence of cardiovascular events was approximately 6-fold greater in atrial fibrillation patients with CHA₂DS₂-VASc scores ≥2, independent of anticoagulation (P_diff=0.45).

AF = atrial fibrillation; CHA₂DS₂-VASc = congestive heart failure or left ventricular ejection fraction ≥0.40, hypertension, age ≥75 or 65–74 yr, diabetes mellitus, vascular disease, female sex, and prior stroke, transient ischemic attack, or thromboembolism; CI = confidence interval; M-H = Mantel-Haenszel