Figure 7.

pkd2 Mutant embryos do not show increased risk of developmental ICH. (A) Percentage of ICH observed in pkd2^hi4166 mutants, morphants (Mos), and their control siblings (n=3 with an average of 100 embryos in each repeat). No significant difference was detected. (B) Percentage of ICH in pkd2^hi4166 mutants and control siblings treated with cyclopamine (n=3 with an average of 20 embryos in each repeat). Vehicle-treated embryos did not show any hemorrhage. No significant difference is detected between mutants and control siblings. *P<0.05 between cyclopamine- and vehicle-treated groups.