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. 2014 Nov 7;26(4):976–985. doi: 10.1681/ASN.2014010046

Table 4.

eGFR (milliliters per minute per 1.73 m2) by MDRD at baseline and 6, 12, and 18 months stratified by baseline eGFR

Mean (SEM) eGFR, ml/min per 1.73 m2 RTX Group (n=51) CYC/AZA Group (n=51) P Value
Baseline eGFR>60 9 10
 Baseline 80.1 (8.40) 76.6 (6.01) 0.74
 6 mo 78.7 (7.50) 76.4 (5.33) 0.81
 12 mo 77.3 (6.84) 76.2 (4.80) 0.90
 18 mo 75.9 (6.52) 76.0 (4.46) 0.99
 Comparison between 18 mo and baseline, P value <0.01 0.20
 Treatment difference over time, P value 0.54
Baseline eGFR=30–60 24 20
 Baseline 39.5 (2.10) 46.6 (2.31) 0.03
 6 mo 42.9 (2.49) 50.5 (2.72) 0.05
 12 mo 46.4 (3.24) 54.4 (3.51) 0.10
 18 mo 49.9 (4.16) 58.3 (4.50) 0.18
 Comparison between 18 mo and baseline, P value <0.01 <0.01
 Treatment difference over time, P value 0.80
Baseline eGFR<30 18 14
 Baseline 24.4 (1.66) 25.5 (1.88) 0.66
 6 mo 26.3 (2.22) 28.0 (2.50) 0.61
 12 mo 28.1 (3.32) 30.5 (3.73) 0.64
 18 mo 30.0 (4.58) 33.0 (5.14) 0.67
 Comparison between 18 mo and baseline, P value <0.01 0.09
 Treatment difference over time, P value 0.77