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. 2015 Feb 19;59(1):2459. doi: 10.4081/ejh.2015.2459

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©Copyright A. Di Vito et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Immunohistochemical results of elastofibroma. A) Immunostaining for periostin in peripheral vascularized part of elastofibroma; note the staining of an angiogenetic perivascular tuft of cells, sign of an endothelial-mesenchymal transition (arrow). B) Immunostaining for periostin in the central area of elastofibroma; note the lower positivity for periostin in the stroma. C) Strong staining for periostin is observed in ligamentum flavum. D) Immunostaining for tenascin-C in elastofibroma; tenascin-C positivity in the stroma and cells scattered in central part of elastofibroma (arrows); perivascular positivity for tenascin-C is also observed in the peripheral part of the lesion (not shown).