Table 2.
Distribution of other major birth defects for Florida-born children with non-isolated orofacial clefts, 1998–2006
| Cleft lip with cleft palate (n=363) |
Cleft lip (n=45) |
Cleft palate (n=266) |
|
|---|---|---|---|
| Accompanying defecta | N (%) | N (%) | N (%) |
| Congenital heart defects | 230 (63.4) | 26 (57.8) | 157 (59.0) |
| Musculoskeletal defects | 135 (37.2) | 16 (35.6) | 163 (61.3) |
| Chromosomal abnormalities | 87 (24.0) | 6 (13.3) | 59 (22.2) |
| Genitourinary defects | 69 (19.0) | 6 (13.3) | 60 (22.6) |
| Congenital lung abnormalities | 54 (14.9) | 5 (11.1) | 33 (12.4) |
| Eye/Ear defects | 48 (13.2) | 14 (31.1) | 28 (10.5) |
| Gastrointestinal defects | 47 (13.0) | NR | 48 (18.1) |
| Central nervous system defects | 11 (3.0) | NR | 8 (3.0) |
Notes: Orofacial clefts sub-types are mutually exclusive; Non-isolated= International Classification of Disease, 9th revision; Clinical Modification (ICD-9-CM) codes for other major birth defects present in the Florida Birth Defects Registry, including syndromes.
NR: not reported due to cell counts of < 5.
Birth defect groups are not mutually exclusive- ICD-9-CM codes used: congenital heart defects (745.00–747.90), musculoskeletal defects (754.00–756.90), chromosomal abnormalities (758.00–758.90), genitourinary (752.00 – 753.90), congenital lung abnormalities (748.00-478.90), eye/ear defects (743.00–744.90) gastrointestinal (750.00–751.90), central nervous system (740.00 –742.90).