Table 1. Characteristics of study population, N=4,994.
| Patients N=3,635 N (%) | Controls N=1,359 N (%) | P-value | |
|---|---|---|---|
| Countries | |||
| Belgium | 248 (6.8) | 131 (9.6) | — |
| Denmark | 256 (7.0) | 122 (9.0) | — |
| France | 114 (3.1) | 20 (1.5) | — |
| Germany | 278 (7.6) | 133 (9.8) | — |
| Hungary | 250 (6.9) | 134 (9.9) | — |
| Italy (two centers) | 499 (13.7) | 46 (3.4) | — |
| Netherlands | 213 (5.9) | — | — |
| Norway (two centers) | 527 (14.5) | 218 (16.0) | — |
| Poland | 250 (6.9) | 125 (9.2) | — |
| Russia | 248 (6.8) | 120 (8.8) | — |
| Spain | 249 (6.9) | 116 (8.5) | — |
| Turkey | 250 (6.9) | 109 (8.0) | — |
| UK | 253 (7.0) | 85 (6.3) | — |
| Gender (MD=17) | |||
| Females | 2,045 (56.5) | 903 (66.6) | <0.001 |
| Age years Mean SD (MD=91) | 47.2 (SD=17.9) | 41.1 (SD=13.6) | <0.001 |
| Females | 46.0 (SD=17.6) | 41.1 (SD=13.3) | <0.001 |
| Males | 48.6 (SD=18.2) | 41.1 (SD=14.2) | <0.001 |
| Marital status (MD=322) | |||
| Single | 863 (26.0) | 362 (26.7) | <0.001 |
| Married/partner | 1,978 (59.6) | 840 (62.0) | — |
| Separated/divorced | 273 (8.2) | 119 (8.8) | — |
| Widowed | 203 (6.1) | 34 (2.5) | — |
| Self-reported socioeconomic level (MD=106) | |||
| Low | 644 (18.2) | 215 (15.9) | 0.183 |
| Middle | 2,589 (73.1) | 1,012 (75.1) | — |
| High | 307 (8.7) | 121 (9) | — |
| Stressful life events during last 6 months (MD=97) | |||
| Yes | 1,262 (35.6) | 412 (30.6) | <0.001 |
| Physical co-morbidities1 (MD=479) | |||
| Yes | 993 (28.8) | 170 (16.0) | <0.001 |
Abbreviation: MD, missing data.
1
Physical co-morbidities: any treated cardio-vascular, chronic respiratory, diabetes, or rheumatologic disease.