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Histone-fold heterodimers in the nucleosome core particle structure. (a) Nucleosome core particle structure with central H3/H4 histone-fold tetramer shown in blue (H3) and green (H4). H3 and H4 extensions are shown in light blue and light green, respectively. (b) Nucleosome core particle structure with one H2A/H2B histone-fold dimer shown in yellow (H2A) and red (H2B). H2A and H2B extensions are shown in light yellow and pink, respectively.
