Figure 9.

RNA polymerase II blocking by nucleosome positioning sequences. Sequences of NCP601, NCP603, and NCP605 sequences and their reversed counterparts together with ability to block RNA polymerase II.⁷³ Multiple TA steps bound to the H3/H4 tetramer downstream (red) of the dyad (purple) blocks RNA polymerase II passage as compared with upstream (blue) of the dyad. TA steps bound to the H2A/H2B dimers are shown in orange. The sequence shown for the 601 sequence is the reverse complement of what is shown in Figure 6 to be consistent with ref (73).