Table 5.
Haematological results on day 15 of oral gavage administration of 500, 1000, 1500, and 2000 mg/Kg B.Wt. of SIE to female CF rats. NS represent no statistical significant differences, when the test groups were compared to the control group.
| Parameter | Control group | 500 mg/Kg B.Wt. | 1000 mg/Kg B.Wt. | 1500 mg/Kg B.Wt. | 2000 mg/Kg B.Wt. | P value | |
|---|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |||
| 1 | Hgb (g/dL) | 12.63 ± 0.50 | 12.68 ± 0.66 | 13.16 ± 0.38 | 13.16 ± 1.00 | 12.80 ± 0.80 | NS |
| 2 | T-RBC (×106/mm3) | 6.76 ± 0.26 | 5.99 ± 0.49 | 5.99 ± 0.49 | 6.72 ± 0.49 | 6.44 ± 0.82 | NS |
| 3 | MCV (micron3) | 56.90 ± 2.10 | 57.08 ± 1.56 | 57.42 ± 1.78 | 54.75 ± 1.81 | 55.02 ± 1.77 | NS |
| 4 | HCT (%) | 38.47 ± 0.37 | 34.23 ± 2.06 | 34.40 ± 2.73 | 36.80 ± 2.88 | 35.35 ± 3.30 | NS |
| 5 | MCH (pg) | 20.33 ± 1.25 | 21.15 ± 0.37 | 22.12 ± 1.42 | 19.60 ± 1.10 | 20.00 ± 1.64 | NS |
| 6 | MCHC (g/dL) | 35.67 ± 1.01 | 37.08 ± 0.41 | 38.48 ± 1.94 | 35.85 ± 1.00 | 36.32 ± 2.24 | NS |
| 7 | WBC ×103 | 5.35 ± 1.03 | 5.07 ± 0.76 | 4.88 ± 1.22 | 5.08 ± 1.95 | 5.32 ± 1.05 | NS |
| 8 | RDW | 8.87 ± 1.32 | 10.45 ± 0.33 | 9.40 ± 0.96 | 8.67 ± 1.02 | 10.81 ± 1.42 | NS |
| 9 | MPV | 4.00 ± 0.36 | 4.02 ± 0.33 | 4.26 ± 0.09 | 4.45 ± 0.13 | 4.24 ± 0.09 | NS |
| 10 | PLT (×103/mm3) | 736.3 ± 47.20 | 759.0 ± 67.56 | 750.8 ± 84.40 | 796.8 ± 39.34 | 742.4 ± 74.48 | NS |