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. Author manuscript; available in PMC: 2015 Mar 30.
Published in final edited form as: Curr Alzheimer Res. 2014;11(9):892–898.

Fig. (1).

Fig. (1)

H2O2-induced death of peripheral lymphocytes from AD patients correlated with the degree of dementia severity. Lymphocytes from 10 severe dementia AD patients (CDR 3) (squares), 13 mild-to-moderate AD (CDR 1–2) (triangles), and 15 healthy controls (rhomboids) were exposed to H2O2 for 20 h and cell death was determined by flow cytometry and propidium iodide staining. A: Survival values. Means ± S.E. * =AD CDR 3 vs HC; # =AD CDR 1–2 vs HC; α =AD CDR 3 vs AD CDR1–2. One symbol: p<0.05; 2 symbols: p<0.005; 3 symbols: p<0.0001. Inset: Lymphocyte survival values (%, mean ± SEM) measured at 100 µM H2O2, in the three groups of patients. B: Survival values measured at 100 µM H2O2 in lymphocytes from individual participants plotted against their MMSE scores. Kendall’s tau-b 2-tailed correlation (0.389; p<0.001). Symbols as in (A).