Table 4.
Percent of embryos exhibiting specific lesions on different developmental days in Critical Period: Study A
| Duration of Exposure | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Day 2 Lesions | Control | 0–120hpf | 15–120hpf | 24–120hpf | 30–120hpf | 48–120hpf |
| Reduced Circulating RBCs | - | 16 | - | - | - | - |
| Pericardial Edema | - | - | - | - | - | - |
| Pooled Blood in CCV | - | 44* | 36* | 32* | 16 | 16 |
| Cranial Hemorrhage | - | - | - | - | - | - |
| Abnormal ISVs | - | - | - | - | - | - |
| Duration of Exposure | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Day 3 Lesions | Control | 0–120hpf | 15–120hpf | 24–120hpf | 30–120hpf | 48–120hpf |
| Reduced Circulating RBCs | - | - | 4 | - | - | - |
| Pericardial Edema | - | 4 | - | 4 | 4 | - |
| Pooled Blood in CCV | - | 4 | - | - | - | - |
| Cranial Hemorrhage | - | 36* | 44* | 32 | 28 | 16 |
| Abnormal ISVs | - | - | - | - | - | - |
| Duration of Exposure | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Day 4 Lesions | Control | 0–120hpf | 15–120hpf | 24–120hpf | 30–120hpf | 48–120hpf |
| Reduced Circulating RBCs | - | 4 | 4 | 12 | 8 | 4 |
| Pericardial Edema | - | - | - | 4 | 16 | - |
| Pooled Blood in CCV | - | - | - | - | - | - |
| Cranial Hemorrhage | - | 12 | 12 | 20 | 20 | 12 |
| Abnormal ISVs | - | 44* | 48* | 44* | 24 | 12 |
Values in table are percentages (N = 25)
*
Significantly different from control (P ≤ 0.05)