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Individual antibiotic class limitation in RTI management
| Class | Limitation |
|---|---|
| β-lactam | No activity against atypical pathogen and development of S. pneumoniae resistant isolates > 50 % |
| Macrolides | 30.9 % resistant S. pneumoniae isolates reported |
| Fluroquinolones | Increase potential for emergence of resistant strain of gram negative microorganism |
