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. 2015 Mar 30;10(3):e0121912. doi: 10.1371/journal.pone.0121912

Fig 3. Comparison of in vitro cytotoxicity with ATO of NAPL Vs. RAPL and other cell lines.

Fig 3

Scatter plots of the IC50 values of newly diagnosed patients (N = 61) and relapsed patients (N = 23) after treating with ATO concentrations ranging from 0.1 to 6 μM for 48 hours is shown. The median IC50 of the newly diagnosed (4.41 μM) and relapse group (3.51 μM) was not significantly different and was higher when compared to that of NB4 cell line (N = 16). The median IC50 of NB4 was 0.9 μM, while that of NB4-EV-AsR1 (ATO resistant NB4 cell line) was 3.25 μM. The IC50 of HL60 was 4.25 μM.