Table 2.

Size and peak z-values of the significant clusters in the group analyses

Contrast	Brain Regions	# of Voxels	MNI Coordinates of Peak Voxel (x, y, z)	Peak z-value	Cluster mean z-value ± Standard Deviation
Controls>MDD	Total cluster	1831	51, 57, 21	5.00	Controls: 1.70 ± 0.67 MDD: 0.75 ± 0.83
	Left hippocampus	143
	Left parahippocampus	274
	Brainstem	362
	Left orbitofrontal cortex	46
	Left temporal pole	34
	Left temporal fusiform	247
MDD> Controls	Bilateral precuneus	682	43, 27, 62	4.30	Controls: −0.79 ± 1.1 MDD: 0.26 ± .89