Table 5.
Tumor marker positivity | HIV-infected patients | HIV-uninfected patients | ||
---|---|---|---|---|
Bivariate analyses (crude) | ||||
OR (95% CI) | P | OR (95% CI) | P | |
cMYC | 2.36 (0.87–6.42) | 0.09 | 2.05 (0.61–6.90) | 0.25 |
P27 | 1.61 (0.63–4.10) | 0.32 | 0.72 (0.19–2.65) | 0.62 |
BCL6 | 0.45 (0.18–1.15) | 0.10 | —a | |
PKC-β2 | 0.86 (0.34–2.19) | 0.75 | 11.58 (0.97–138.76) | 0.05 |
MUM1 | 1.63 (0.65–4.07) | 0.30 | 2.10 (0.48–9.30) | 0.33 |
CD44 | 0.32 (0.08–1.27) | 0.11 | 1.98 (0.55–7.09) | 0.29 |
Multivariable analyses (adjusted)b | ||||
cMYC | 3.09 (0.90–10.55) | 0.07 | 2.84 (0.54–15.01) | 0.22 |
P27 | 1.44 (0.49–4.22) | 0.50 | 0.18 (0.03–1.27) | 0.08 |
BCL6 | 0.48 (0.12–1.87) | 0.29 | —a | |
PKC-β2 | 0.54 (0.17–1.69) | 0.29 | 3.93 (0.19–83.28) | 0.38 |
MUM1 | 0.90 (0.29–2.79) | 0.85 | 0.80 (0.10–6.54) | 0.83 |
CD44 | 0.18 (0.04–0.89) | 0.04 | 1.52 (0.28–8.25) | 0.63 |
OR cannot be estimated due to rare marker expression.
Model adjusted for IPI, germinal center phenotype, DLBCL subtype, and receipt of chemotherapy. Gender and race were matched and thus did not require adjustment in the multivariable model.