Table 1. Class versus nonclass comparison of traits for the k = 4 and k = 5 adult CF clinical phenotypes.

	MDCP Class	PS	CFTR Class IV, V VI	PA	Candida	PA/Candida	MSSA/ASP	Interpretation
k = 4	A	<.05 (p = .002)						Low A*FEV1
	B			2.7 (p = .04)				Low A*FEV1, older, male
	C		.27(p = .05)	.37 (p = .05)			4.2(p = .03)	Median A*FEV1, female
	D	5.0 (p = .0007)	3.2(p = .01)					High A*FEV1, older, male
k = 5	A		<.05(p = .04)	4.9 (p = .03)	4.4 (p = .005)	4.4(p = .01)		Low A*FEV1
	B			3.5 (p = .02)				Low A*FEV1, older, male
	C			.25 (p = .001)			4.5(p = .03)	Median A*FEV1, female
	D	5.2 (p = .0003)	3.4(p = .01)		.17 (p = .005)	.20(p = .01)		High A*FEV1, older, male
	E							Low A*FEV1, female

Entries are the significant Fisher exact test odds ratios (p-values corrected for multiple testing) for pancreatic sufficiency (PS), presence of at least one CFTR class IV, V and VI mutation, Pseudomonas spp (PA), Candida spp, as well as combinations of PA and Candida spp. (PA/Candida) and MSSA and Aspergillus spp. (MSSA/Asp).