. 2015 Mar 30;11(3):e1005109. doi: 10.1371/journal.pgen.1005109

Table 1. Genes identified in esp1-1 SL and SDL screens implicated in Ty1 and Ty3 transposition.

ORF	Gene	esp1-1 screen	Ty1	Ty3
YIL040W	APQ12 ^a	SL	Promote
YNL242W	ATG2 ^k	SL		Inhibit
YBR068C	BAP2 ^a	SL	Promote
YDL074C	BRE1 ^b ^, ^k	SL	Inhibit	Inhibit
YAL021C	CCR4 ^a	SL	Promote
YPR119W	CLB2 ^k	SL		Inhibit
YJL006C	CTK2 ^k	SL		Promote
YCL016C	DCC1 ^c	SL	Promote
YFL001W	DEG1 ^k	SL		Promote
YDL160C	DHH1 ^a ^, ^d ^, ^k	SDL	Promote	Promote
YBR269C	FMP21 ^k	SL		Inhibit
YOR202W	HIS3 ^a	SL	Promote
YGL194C	HOS2 ^e	SL	Promote
YDL115C	IWR1 ^c	SL	Promote
YPL125W	KAP120 ^k	SL		Promote
YOR123C	LEO1 ^b	SL	Inhibit
YPL055C	LGE1 ^a	SL	Promote
YJL124C	LSM1 ^a ^, ^c ^, ^d	SL	Promote
YPR164W	MMS1 ^b	SL	Inhibit
YLR320W	MMS22 ^a ^, ^b ^, ^c	SL	Promote/Inhibit
YMR224C	MRE11 ^b ^, ^f	SL	Inhibit
YGL221C	NIF3 ^a	SL	Promote
YPR164W	NUT2 ^f	SL	Inhibit
YCR077C	PAT1 ^c ^, ^d	SDL	Promote
YJR043C	POL32 ^a	SL	Promote
YKL113C	RAD27 ^b	SDL	Inhibit
YNL250W	RAD5 ^b ^, ^f ^, ^g	SL	Inhibit
YGL163C	RAD54 ^b ^, ^g	SL	Inhibit
YDR156W	RPA14 ^b	SL	Inhibit
YNL069C	RPL16B ^a ^, ^c	SL	Promote
YHR010W	RPL27A ^a	SL	Promote
YFL036W	RPO41 ^a	SL	Promote
YHR021C	RPS27B ^a	SL	Promote
YGL244W	RTF1 ^b ^, ^c	SL	Promote/Inhibit
YLL002W	RTT109 ^b ^, ^f ^, ^k	SL	Inhibit	Inhibit
YMR190C	SGS1 ^b ^, ^f ^, ^k	SDL	Inhibit	Inhibit
YJL089W	SIP4 ^a	SDL	Promote
YGR229C	SMI1 ^c	SL	Promote
YCR033W	SNT1 ^a	SL	Promote
YJL127C	SPT10 ^a ^, ^c ^, ^h	SDL	Promote
YKL020C	SPT23 ^a ^, ⁱ	SDL	Promote
YOR212W	STE4 ^j	SDL	Inhibit
YPL157W	TGS1 ^a	SL	Promote
YPR133W-A	TOM5 ^a	SL	Promote
YNL299W	TRF5 ^a	SL	Promote
YDR200C	VPS64 ^b	SL	Inhibit
YDR369C	XRS2 ^c	SL	Promote
YDR290W	YDR290W ^k	SL		Inhibit

^aMutants that suppress the hypertransposition phenotype of rtt101Δ and med1Δ mutants [45]

^bMutants that increase the Ty1 transposition frequency [42]

^cAll mutants have decreased Ty1 transposition except for 2 (YML105C and YOL159C) [40]

^dP-body components encoded by DHH1, KEM1, LSM1, and PAT1 act as cofactors that posttranscriptionally enhance Ty1 retrotransposition [44]

^eDeletion of HOS2 or SET3 reduces Ty1 transposition [101]

^f rtt mutants have increased levels of Ty1 transposition [43]

^g rad50, rad51, rad52, rad54 and rad57 mutants have increased Ty1 transposition [58]

^h spt mutants suppress lys2-128δ and his4-917 Ty insertion mutations [49]

ⁱ SPT23 is a high copy suppressor of the his4-912δ and lys2-61 Ty induced Promoter mutations [48]

^jThe mating pheromone-response pathways suppresses Ty1 transposition[102]

^kMutants that increase or decrease Ty3 transposition frequency [41]