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. 2015 Mar 30;10(3):e0119513. doi: 10.1371/journal.pone.0119513

Table 4. Results of multivariate analyses for factors associated with 6 clinical signs of virus positive in outpatients, Shanghai, China*, 2011–2013.

Clinical sign of ILI§.
Factors Cough Sore throat Running nose
Yes, n = 494 No, n = 144 OR(95% CI),p value Yes, n = 347 No, n = 291 OR(95% CI),p value Yes, n = 309 No, n = 329 OR(95% CI),p value
other viral positive 174 (35.2) 71 (49.3) Ref 133 (38.3) 112 (38.5) Ref 109 (35.3) 136 (41.3) Ref
Flu viral positive 320 (64.8) 73 (50.7) 1.99(1.60–2.47),<0.001 214 (61.7) 179 (61.5) 1.22(1.01–1.48), 0.038 200 (64.7) 193 (58.7) 1.62(1.34–1.96), <0.001
Age<5y 95 19.2) 10 (6.9) 3.22(2.34–4.42), <0.001 39 (11.2) 66 (22.7) 0.39(0.31–0.50), <0.001 62 (20.1) 43 (13.1) 1.90(1.50–2.41), <0.001
Male 243 (49.2) 71 (49.3) 1.08(0.89–1.31),0.432 169 (48.7) 145 (49.8) 0.96(0.81–1.15),0.682 152 (49.2) 162 (49.2) 0.99(0.83–1.19),0.907
Interval 2d# 38 7.7 10(6.9) 1.38(0.94–2.01),0.102 298.4 196.5 1.71(1.21–2.42), 0.002 247.8 247.3 0.99(0.70–1.40),0.955
Factors Fatigue Headache Temperature
Yes, n = 228 No, n = 410 OR(95% CI),p value Yes, n = 199 No, n = 439 OR(95% CI),p value >39°C, n = 102 ≤39°C, n = 534 OR(95% CI),p value
other viral positive 67 (29.4) 178 (43.4) Ref 60 (30.2) 185 (42.1) Ref 2322.5 22241.6 Ref
Flu viral positive 161 (70.6) 232 (56.6) 1.25(1.02–1.53), 0.028 139 (69.8) 254 (57.9) 1.24(1.01–1.52),0.043 7977.5 31258.4 1.40(1.07–1.83),0.015
Age<5y 10.4 104(25.4) 0.020.01–0.05), <0.001 1 (0.5) 104(23.7) 0.010.003–0.05), <0.001 1918.6 8616.1 1.31(0.95–1.82), 0.104
Male 111 (48.7) 203(49.5) 0.96(0.79–1.16),0.662 99 (49.7) 215 (49.0) 0.92(0.76–1.12),0.413 45 (44.1) 268 (50.2) 0.95(0.73–1.23),0.682
Interval 2d# 33 (14.5) 15 (3.7) 3.15(2.24–4.43),<0.001 26 (13.1) 225.0 2.04(1.45–2.87), <0.001 87.8 407.5 0.830.49–1.390.474

*Six multivariate unconditional logistic regression analyses were separately conducted to examine factors for each clinical sign of ILI. ILI outpatients from whom influenza viral were detected positive by RT-PCR as confirmed influenza patients, and from whom other respiratory viral were detected positive by RT-PCR as confirmed other respiratory viral infection patients. Boldface font indicates statistical. OR, odds ratio; Ref, reference.

§Data are number (%) outpatients unless otherwise indicated.

#Interval between illness onset and hospital visit.

※Total of 2(0.2%)outpatients missing information on temperature results in the Influenza virus positive ILI-case group.