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. 2015 Mar 30;10(3):e0119687. doi: 10.1371/journal.pone.0119687

Fig 2. Analysis of TFAM and Twinkle (TW) mice 8 weeks after arteriovenous fistula creation.

Fig 2

(A) Heart weight/body weight (HW/BW) (n = 12) (B) M-mode echocardiogram (C) Lung weight/body weight (LW/BW) in TFAM and TW mice (n = 12). (D) Quantification of perivascular fibrosis standardized by vascular circumference (n = 6). (E) mtDNA copy number in left ventricle (LV) of TFAM (upper panel) and TW (lower panel) mice (n = 6). (F) Mitochondrial electron transport chain enzymatic activities in TFAM (upper panel) and TW (lower panel) mice (n = 4–5). Data are expressed as mean ± SEM. *P < 0.05 vs. WT + Sham, **P < 0.01 vs. WT + Sham, † P < 0.01 vs. WT + VO, †† P < 0.01 vs. WT + VO, analyzed by one-way ANOVA followed by post hoc Tukey’s test.