Table 1. Metabolites with significant concentration changes due to the pre-storage handling conditions of the samples.
| Metabolite name | Short name | Molecule class | p-value of linear regression model 1 | Direction of change | ||
|---|---|---|---|---|---|---|
| time | temp | time:temp | ||||
| Decadienylcarnitine | C10:2 | Acylcarnitine | 0.578 | 2.00E-05 | 0.174 | - |
| Arginine | Arg | Amino acid | 0.016 | 1.05E-05 | 9.98E-05 | + |
| Glycine | Gly | Amino acid | 1.55E-04 | 2.27E-10 | 1.50E-07 | + |
| Ornithine | Orn | Amino acid | 0.074 | 5.96E-10 | 2.49E-07 | + |
| Phenylalanine | Phe | Amino acid | 1.17E-07 | 4.87E-14 | 1.48E-12 | + |
| Serine | Ser | Amino acid | 7.51E-07 | 3.58E-15 | 7.58E-14 | + |
| Leucine+Isoleucine | Leu+Ile | Amino acid | 0.204 | 6.41E-06 | 0.001 | + |
| Lysophosphatidylcholine LPC(14:0) | lysoPC(14:0) | Glycerophospholipid | 1.84E-09 | 6.32E-18 | 1.58E-24 | + |
| Lysophosphatidylcholine LPC(16:0) | lysoPC(16:0) | Glycerophospholipid | 3.93E-24 | 1.65E-25 | 2.94E-51 | + |
| Lysophosphatidylcholine LPC(16:1) | lysoPC(16:1) | Glycerophospholipid | 1.24E-09 | 3.60E-18 | 2.02E-23 | + |
| Lysophosphatidylcholine LPC(17:0) | lysoPC(17:0) | Glycerophospholipid | 2.32E-17 | 1.41E-21 | 1.17E-40 | + |
| Lysophosphatidylcholine LPC(18:0) | lysoPC(18:0) | Glycerophospholipid | 1.05E-25 | 1.09E-25 | 3.64E-53 | + |
| Lysophosphatidylcholine LPC(18:1) | lysoPC(18:1) | Glycerophospholipid | 3.17E-10 | 1.90E-21 | 3.39E-31 | + |
| Lysophosphatidylcholine LPC(20:0) | lysoPC(20:3) | Glycerophospholipid | 3.02E-05 | 8.71E-15 | 1.01E-14 | + |
| Lysophosphatidylcholine LPC(20:4) | lysoPC(20:4) | Glycerophospholipid | 2.85E-05 | 6.38E-14 | 3.62E-17 | + |
| Diacylphosphatidylcholine PC(30:0) | PC(30:0) | Glycerophospholipid | 0.021 | 3.00E-06 | 1.14E-05 | - |
| Diacylphosphatidylcholine PC(32:0) | PC(32:0) | Glycerophospholipid | 0.141 | 5.70E-05 | 0.015 | - |
| Diacylphosphatidylcholine PC(32:1) | PC(32:1) | Glycerophospholipid | 7.80E-10 | 7.94E-12 | 7.34E-19 | - |
| Diacylphosphatidylcholine PC(32:2) | PC(32:2) | Glycerophospholipid | 0.002 | 4.52E-08 | 3.87E-09 | - |
| Diacylphosphatidylcholine PC(34:2) | PC(34:2) | Glycerophospholipid | 0.005 | 4.72E-06 | 7.78E-05 | - |
| Diacylphosphatidylcholine PC(34:3) | PC(34:3) | Glycerophospholipid | 4.75E-05 | 1.04E-10 | 3.11E-11 | - |
| Diacylphosphatidylcholine PC(34:4) | PC(34:4) | Glycerophospholipid | 0.008 | 1.61E-05 | 0.004 | - |
| Diacylphosphatidylcholine PC(36:5) | PC(36:5) | Glycerophospholipid | 0.009 | 6.17E-05 | 0.001 | - |
| Acylalkylphosphatidylcholine PC(O-34:1) | PC(O-34:1) | Glycerophospholipid | 0.086 | 4.65E-05 | 0.027 | - |
1: metabolites displayed significant p-values (in bold) of the linear regression model either for temperature alone (temp), for temperature and interaction (time:temp) or for time (time), temperature and interaction; the column on the right indicates the direction of the observed concentration changes.