. 2015 Mar 30;10(3):e0122363. doi: 10.1371/journal.pone.0122363

Table 3. Registration errors obtained after random misalignments of the images in relation with its original spatially normalized position.

				Translate						Rotate						Scale						All
Test	Strain	Condition		Mean	±	SD	Min	-	Max	Mean	±	SD	Min	-	Max	Mean	±	SD	Min	-	Max	Mean		SD	Min	±	Max
Standard template test:
[¹¹C]Flumazenil	Wistar (n = 13)	Tracer specific template		0.22	±	0.09	0.08	-	0.48	0.21	±	0.10	0.08	-	0.54	0.25	±	0.10	0.08	-	0.52	0.23	±	0.10	0.09	-	0.58
		FDG template		0.94	±	0.22	0.35	-	1.25	1.07	±	0.30	0.48	-	2.03	1.07	±	0.28	0.53	-	1.63	1.84	±	1.90	0.66	-	9.42
[¹¹C]MeDAS	Wistar (n = 15)	Tracer specific template		0.89	±	0.19	0.29	-	1.21	0.84	±	0.20	0.23	-	1.19	0.92	±	0.22	0.28	-	1.29	0.86	±	0.22	0.23	-	1.29
		FDG template		1.31	±	0.33	0.60	-	2.12	1.06	±	0.32	0.46	-	2.16	1.66	±	0.48	0.69	-	3.41	1.68	±	0.90	0.61	-	6.08
[¹¹C]PK11195	Wistar (n = 19)	Tracer specific template		0.65	±	0.27	0.16	-	1.16	0.57	±	0.24	0.16	-	1.01	0.72	±	0.32	0.18	-	1.68	0.63	±	0.29	0.17	-	2.15
		FDG template		6.77	±	4.17	0.92	-	20.18	8.47	±	3.38	1.10	-	40.91	7.61	±	5.80	0.79	-	22.69	8.77	±	5.13	1.37	-	37.14
[¹¹C]Raclopride	Wistar (n = 6)	Tracer specific template		0.33	±	0.13	0.16	-	0.56	0.33	±	0.16	0.14	-	0.65	0.34	±	0.14	0.16	-	0.67	0.33	±	0.17	0.14	-	0.68
		FDG template		2.13	±	0.56	1.26	-	3.73	2.77	±	0.95	1.60	-	6.60	2.53	±	0.66	0.97	-	4.56	2.96	±	1.09	1.68	-	6.68
[^99mTc]HMPAO	Wistar (n = 15)	Tracer specific template		0.40	±	0.12	0.22	-	0.91	0.38	±	0.13	0.24	-	0.94	0.42	±	0.16	0.23	-	1.26	0.39	±	0.13	0.22	-	0.92
		FDG template		1.10	±	0.26	0.40	-	2.25	0.98	±	0.30	0.37	-	1.93	1.32	±	0.41	0.47	-	2.53	1.39	±	0.84	0.34	-	5.49
Strain test:
[¹⁸F]FDG	Sprague-Dawley (n = 9)	Specific		0.40	±	0.17	0.17	-	0.97	0.38	±	0.26	0.17	-	1.74	0.47	±	0.21	0.19	-	1.25	0.67	±	0.69	0.18	-	3.53
		Other		0.79	±	0.16	0.48	-	1.25	0.70	±	0.20	0.26	-	1.29	0.86	±	0.26	0.44	-	1.96	0.81	±	0.35	0.39	-	2.56
		Both		0.60	±	0.17	0.32	-	1.11	0.53	±	0.18	0.27	-	0.98	0.73	±	0.24	0.33	-	1.40	0.77	±	0.63	0.25	-	3.61
	Wistar (n = 25)	Specific		0.71	±	0.30	0.23	-	1.36	0.63	±	0.25	0.22	-	1.28	0.77	±	0.36	0.23	-	2.36	0.69	±	0.38	0.22	-	3.43
		Other		1.14	±	0.39	0.64	-	2.59	1.17	±	0.43	0.67	-	3.13	1.20	±	0.45	0.61	-	3.03	1.36	±	0.56	0.65	-	3.25
		Both		0.79	±	0.39	0.26	-	1.69	0.74	±	0.36	0.24	-	1.80	0.87	±	0.47	0.22	-	2.39	0.94	±	0.58	0.23	-	3.09
[¹¹C]PK11195	Sprague-Dawley (n = 11)	Specific		0.57	±	0.33	0.19	-	1.61	0.50	±	0.33	0.25	-	1.62	0.66	±	0.36	0.27	-	1.74	0.56	±	0.36	0.22	-	1.84
		Other		0.91	±	0.21	0.40	-	1.19	0.80	±	0.19	0.34	-	1.14	1.01	±	0.28	0.30	-	1.74	0.85	±	0.25	0.33	-	1.39
		Both		0.80	±	0.22	0.31	-	1.23	0.71	±	0.21	0.26	-	1.21	0.91	±	0.29	0.28	-	1.53	0.78	±	0.29	0.22	-	1.81
	Wistar (n = 19)	Specific		0.63	±	0.26	0.16	-	1.16	0.58	±	0.24	0.16	-	1.00	0.71	±	0.32	0.18	-	1.92	0.63	±	0.29	0.16	-	2.07
		Other		0.96	±	0.21	0.47	-	1.47	0.92	±	0.23	0.50	-	1.53	1.08	±	0.36	0.47	-	2.75	0.94	±	0.25	0.46	-	1.66
		Both		0.65	±	0.23	0.18	-	1.05	0.59	±	0.20	0.12	-	0.97	0.72	±	0.27	0.20	-	1.68	0.65	±	0.30	0.18	-	3.03
Size test:
[¹⁸F]FDG	Wistar (n = 25)	Small image	Template same size	0.71	±	0.30	0.21	-	1.36	0.63	±	0.25	0.22	-	1.19	0.78	±	0.37	0.22	-	2.15	0.71	±	0.42	0.21	-	3.43
			Template different size	1.99	±	0.51	1.08	-	3.51	2.70	±	0.28	1.30	-	3.64	2.23	±	0.74	0.83	-	8.51	2.89	±	0.94	2.08	-	13.24
		Large image	Template same size	0.87	±	0.26	0.39	-	1.53	0.87	±	0.30	0.27	-	1.70	0.98	±	0.33	0.29	-	1.74	0.99	±	0.33	0.28	-	1.97
			Template different size	0.96	±	0.34	0.35	-	1.53	0.97	±	0.35	0.29	-	1.65	0.95	±	0.36	0.32	-	2.04	0.97	±	0.37	0.32	-	1.82
[¹¹C]PK11195	Wistar (n = 19)	Small image	Template same size	0.65	±	0.27	0.16	-	1.16	0.57	±	0.24	0.16	-	1.01	0.72	±	0.32	0.18	-	1.68	0.63	±	0.29	0.17	-	2.15
			Template different size	3.66	±	0.68	1.06	-	4.64	4.05	±	0.12	3.78	-	4.36	3.64	±	0.67	0.96	-	4.44	3.95	±	0.44	1.95	-	5.41
		Large image	Template same size	0.62	±	0.19	0.18	-	1.16	0.72	±	0.27	0.21	-	1.46	0.78	±	0.30	0.21	-	1.90	0.76	±	0.27	0.31	-	1.64
			Template different size	0.80	±	0.30	0.20	-	1.28	0.81	±	0.30	0.20	-	1.31	0.83	±	0.31	0.20	-	1.52	0.84	±	0.30	0.18	-	1.45
Intervention tests:
[¹¹C]PK11195	Sprague-Dawley	Injection of saline	Healthy (n = 11)	0.57	±	0.33	0.19	-	1.61	0.50	±	0.33	0.25	-	1.62	0.66	±	0.36	0.27	-	1.74	0.56	±	0.36	0.22	-	1.84
			Intervention (n = 10)	1.08	±	0.21	0.55	-	1.38	1.04	±	0.21	0.53	-	1.37	1.21	±	0.30	0.63	-	2.39	1.09	±	0.29	0.50	-	2.22
	Wistar	Herpes encephalitis model	Healthy (n = 19)	0.63	±	0.26	0.16	-	1.16	0.58	±	0.24	0.16	-	1.00	0.71	±	0.32	0.18	-	1.92	0.63	±	0.29	0.16	-	2.07
			Intervention (n = 14)	0.75	±	0.29	0.19	-	1.38	0.69	±	0.29	0.20	-	1.40	0.82	±	0.31	0.18	-	1.60	0.74	±	0.30	0.18	-	1.57

Units are expressed in millimeters.