Table 5. Registration errors: effect of strain specific template.

	Translate			Rotate			Scale			Combined
	B	95% CI	p-value	B	95% CI	p-value	B	95% CI	p-value	B	95% CI	p-value
(Intercept)	−0.33	−0.46; −0.21	<0.001	−0.43	−0.56; −0.30	<0.001	−0.22	−0.34; −0.11	<0.001	−0.33	−0.45; −0.22	<0.001
Tracer ([18F]FDG)	0.03	−0.12; 0.18	0.718	0.06	−0.10; 0.21	0.471	0.01	−0.14; 0.16	0.916	0.20	0.06; 0.35	<0.001
Strain (Sprague-Dawley)	−0.02	−0.19; 0.15	0.828	−0.06	−0.24; 0.13	0.551	0.03	−0.13; 0.20	0.693	0.00	−0.16; 0.16	0.982
Template (same strain)	−0.08	−0.13; −0.02	0.012	−0.10	−0.17; −0.04	0.003	−0.08	−0.15; −0.02	0.010	−0.18	−0.26; −0.11	<0.001
Template (different strain)	0.37	0.28; 0.46	<0.001	0.45	0.35; 0.55	<0.001	0.36	0.27; 0.44	<0.001	0.37	0.29; 0.46	<0.001
Strain * Template same strain	−0.28	−0.50; −0.07	0.009	−0.24	−0.48; 0.01	0.059	−0.29	−0.48; −0.09	0.004	−0.06	−0.29; 0.16	0.581
Strain * Template different strain	−0.19	−0.29; −0.08	0.001	−0.27	−0.39; −0.15	<0.001	−0.23	−0.33; −0.13	<0.001	−0.31	−0.41; −0.20	<0.001

The test was performed with Sprague-Dawley, [¹⁸F]FDG (n = 9) and [¹¹C]PK11195 (n = 11); and Wistar rats, [¹⁸F]FDG (n = 25) and [¹¹C]PK11195(n = 19). Parameters estimates were obtained using [¹¹C]PK11195, Wistar, and combined template as reference categories.