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. 2015 Mar 30;10(3):e0118616. doi: 10.1371/journal.pone.0118616

Table 1. Clinical features.

Variable N (%)
Time from symptom onset until presentation (days) 52.6±56.4
Underlying pathology
Rheumatic 30 (37)
Prosthetic valve 21 (26)
Normal heart 19 (23.5)
Congenital heart disease 7 (8.6)
Degenerative valve disease 4 (5)
Mitral valve 46 (56.8)
Aortic valve 19 (23.5)
Both valves 13 (16)
VSD, PDA, Ao root 3 (3.7)
Healthcare-associated endocarditis* 25 (30.9)
Organisms
Staph 20 (24.7)
Fungal 8 (10)
Strept 14 (17.3)
Brucella 8 (10)
Culture/serology negative 15 (18.5)
Other 24 (29.6)
Clinically symptomatic neurological complications 34 (42)
Any Major complication** 63 (77.8)
Sepsis requiring ventilation or vasopressor 23 (28.4)
Systemic embolization other than CNS 49 (60.5)
Heart failure 40 (49.4)
Death 15(18.5)

*defined as, 1. Nosocomial infection: infection contracted ≥ 48 hours after hospital admission. 2. Non nosocomial infection: infection appearing ≤ 48 hours of hospital admission within: a) 1 month of receiving IV cannulation, chemotherapy or dialysis; b) 3 months of admission into an acute care facility, c) any time of admission to a nursing home.

**sepsis, major artery embolization, heart failure, death.