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. 2015 Mar 30;10(3):e0120010. doi: 10.1371/journal.pone.0120010

Fig 6. Effect of antagonists of different types of cell death on the PITWT or PIT271 induced cell death.

Fig 6

The proportion of sub-G1 population was evaluated by flow cytometry. Drugs were Z-VAD-FMK (25 μM), a general caspase inhibitor; chloroquine (10 μM), an inhibitor of autophagy; IM-54 (10 μM) and necrostatin-1 (10 μM), inhibitors of necrosis. Flow cytometry was performed 4 days after the addition of the drugs together with 1 μg/ml doxycycline. Results (mean ±SEM) are pooled from two independent experiments, with triplicate measures in each. +: p < 0,05, ++: p < 0,01 relative to the same population without doxycycline; *: p < 0,05, **: p < 0,01 relative to the same condition in the absence of drug.