Table 2. Performance Measures of 3.0-T DWI MRI.
| Observer 1 | Observer 2 | Combined | |
|---|---|---|---|
| Sensitivity,% a | 75.9 (57.9–87.9) b | 69.0 (50.8–82.7) | 72.4 (59.8–82.2) |
| Specificity, % a | 81.5 (63.3–91.8) | 77.8 (59.2–89.4) | 79.6 (67.1–88.2) |
| Overall accuracy % | 78.6 (66.2–87.3) | 73.2(60.4–83.0) | 75.9 (67.2–82.9) |
| Positive predictive value c | 81.5 (61.1–92.5) | 76.9 (55.1–90.0) | 79.2 (66.5–88.0) |
| Negative predictive value c | 75.8 (59.3–87.1) | 70.0 (53.7–82.4) | 72.9 (60.4–82.5) |
| Mean ADC for malignant LN x 10–3 (mm2/s) d , range | 0.688, 0.392–1.323 | 0.689, 0.408–1.091 | 0.689, 0.392–1.323 |
| Mean ADC for benign LN x 10–3 (mm2/s), range e | 1.097, 0.476–2.665 | 1.031, 0.395–1.535 | 1.064, 0.395–2.665 |
Performance Measures of 3.0-T DWI MRI in the Differentiation of Axillary Metastases and the ADCs of Axillary LNs with Histopathologic Diagnosis.
aSensitivity and specificity are calculated with an average cut-off of 0.812 x 10–3 mm2/s.
bData are mean (95% confidence intervals calculated with no-continuity correction Wilson’s formula with a prevalence of 51.8%).
cPositive and negative predictive values were calculated with Bayes’ formula.
dMalignancy reference on whole axillae in ALND.
eSNLB or ALND negative axillary LN with follow-up and contralateral axillary LN.