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. 2015 Mar 30;10(3):e0121977. doi: 10.1371/journal.pone.0121977

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© 2015 Wong et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — One μl of 1 mM CeNPs (172 ng) or saline was delivered to each eye of the animals at P23 and eyes were harvested at 28 dpi; three eyes from 3 individuals were examined per treatment group. (A-D) Representative photomicrographs of H&E stained retinal sections from wildtype, Sprague Dawley (SD) or P23H-1 animals uninjected or treated with either saline or CeNPs. Similar regions were shown: 1 mm from the ONH in the inferior region. (E) shows quantification of the ONL thickness measurements. The overall ONL thickness was higher in CeNPs-treated than in saline-treated animals although the increases were not statistically significant across many of the regions. INL = inner nuclear layer, ONL = outer nuclear layer, I/OS = rod inner/outer segment, ONH = optic nerve head. *P<0.05.