. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Ann Biomed Eng. 2014 Sep 30;43(4):917–928. doi: 10.1007/s10439-014-1137-y

Table III.

Tendon Immunohistochemistry (Col II and Col III)

Tendo n	Gro up	Regi on	Col II			Col III
Tendo n	Gro up	Regi on	2 weeks	4 weeks	8 weeks	2 weeks	4 weeks	8 weeks
Biceps	SD	INS	2 (1–3)	0(0–0)	0(0–1)	1.5 (1–2)	1(1–2)	2(2–2)
	OV		2 (1.5–2)	1(1–2)	1.5(0.75– 2)	0 (0–0.5)	2(1–2)	2(2–2.25)
	SD + OV		1 (1–1)	1(0–1)	0(0–0.25)	0 (0–0.5)*	1(1–1)	2(1–2)
	SD	INT RA	2 (2–3)	0(0–0)	1(0–1)	2 (2–2)	1(1–1)	2(1–2)
	OV		1 (0.5– 1.5)	1(1–1.5)	1(0.75– 1.25)	0 (0–0.5)	1(1–2)	3(2.75–3)
	SD + OV		1 (0.75– 1)	1(1–2)	0(0–1)	0 (0–0)	1(1–1)	2(1–2)
	SD	PRO X	1 (1–3)	0(0–0)	1(1–2)	1(1–1.25)	1(1–2)	2(2–2)
	OV		2 (1–2)	1(1–2)	1(0.75– 1.5)	1(0.5–1)	0(0–1)	2(2–2.25)
	SD + OV		0.5 (0–1)	1(1–1)*	0(0–1)	0(0–0.5)	1(1–1)	1(1–1)^+,**
	SD	DIS	1 (1–2)	1(0–1)	1(0–1)	0(0–0)	1(1–2)	1(0.75– 1.25)
	OV		1 (1–1)	1(1–1)	0(0–0.5)	0(0–0.5)	0(0–1)	1.5(0.75– 2.25)
	SD + OV		1 (0.5– 1.5)	1.5(0.75– 2)	1(1–1)	0(0–0.5)	1(0–1)	1(1–1)
Supra	SD	INS	1 (1–2)	1(1–2)	2(1–3)	0(0–0)	2(1–2)	2(2–2)
	OV		2 (1.5– 2.5)	2(1–3)	1(0.5–1)	0.5(0–1.25)	0(0– 0.25)	3(2–3)
	SD + OV		1 (1–1.5)	0(0–1)	1(0–2)	0(0–0)	0(0–1)*	2(2–2)
	SD	MID	1 (1–1)	1(0–1)	1(1–2)	1(0.75– 1.25)	1(1–2)	2(2–2)
	OV		1 (1–1)	1(1–1)	1(0.5–1.5)	0.5(0–1)	0(0–1)	1(1–1.5)
	SD + OV		1 (1–1)	0(0–0)	0(0–0.5)	0.5(0.25– 0.75)	0(0–0)*	2(1–2)

At 4 weeks, collagen II staining was increased at the biceps proximal groove (PROX) in the SD + OV group compared to SD. Collagen III staining was decreased at the supraspinatus insertion (INS) and mid-substance (MID) in the SD + OV group compared to SD. At 8 weeks, collagen III staining was decreased at the biceps proximal groove in the SD + OV group compared to OV, with a similar trend compared to SD. Data is shown as median and interquartile range (p<0.025, (SD vs. SD + OV*), (OV vs. SD + OV^**), p<0.05 (SD vs. SD+OV⁺)).