Table 1. Trends in lung and bronchus cancer incidence rates in the United States SEER 9 registry in males by race and histology, 1973–2010.
| Trend 1 | Trend 2 | Trend 3 | Trend 4 | |||||
|---|---|---|---|---|---|---|---|---|
| Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | |
| All races | ||||||||
| Small Cell | 1973–1978 | 8.1* (6, 10.2) | 1978–1986 | 2.1* (0.9, 3.3) | 1986–2010 | −2.7* (−2.9, −2.5) | ||
| Squamous Cell | 1973–1981 | 2.6* (1.8, 3.5) | 1981–1990 | −2.0* (−2.9, −1.2) | 1990–2005 | −4.0* (−4.3, −3.6) | 2005–2010 | 0.9 (−0.8, 2.7) |
| Large Cell | 1973–1975 | 25.2* (3.4, 51.5) | 1975–1987 | 1.3* (0, 2.6) | 1987–1998 | −5.8* (−7.2, −4.4) | 1998–2010 | −11.0* (−12, -10) |
| AC | 1973–1979 | 8.4* (6.4, 10.3) | 1979–1992 | 2.2* (1.5, 2.8) | 1992–2005 | −1.7* (−2.3, −1.1) | 2005–2010 | 2.6* (0.2, 5.1) |
| BAC | 1973–1976 | 9.3 (−3.2, 23.4) | 1976–1988 | −3.0* (−4.5, −1.4) | 1988–1993 | 4.8 (−2.9, 13.2) | 1993–2010 | −1.7* (−2.5, −0.9) |
| All Histologies | 1973–1980 | 2.2* (1.6, 2.8) | 1980–1991 | −0.3 (−0.6, 0.1) | 1991–2010 | −1.8* (−2, −1.7) | ||
| White | ||||||||
| Small Cell | 1973–1978 | 8.3* (6.1, 10.6) | 1978–1986 | 2.1* (0.8, 3.4) | 1986–2010 | −2.6* (−2.8, −2.4) | ||
| Squamous Cell | 1973–1980 | 3.0* (1.9, 4.1) | 1980–1988 | −1.3* (−2.4, −0.2) | 1988–2005 | −3.9* (−4.2, −3.5) | 2005–2010 | 1.5 (−0.4, 3.4) |
| Large Cell | 1973–1975 | 23.5* (4.1, 46.6) | 1975–1986 | 1.6* (0.2, 2.9) | 1986–1998 | −5.3* (−6.4, −4.2) | 1998–2010 | −11.1* (−12, −10.2) |
| AC | 1973–1980 | 7.2* (5.6, 8.9) | 1980–1992 | 2.0* (1.2, 2.8) | 1992–2005 | −1.6* (−2.3, −1) | 2005–2010 | 2.1 (−0.5, 4.7) |
| BAC | 1973–1976 | 9 (−3.6, 23.3) | 1976–1989 | −2.5* (−3.9, −1.1) | 1989–1992 | 7.9 (−15.6, 38.1) | 1992–2010 | −1.5* (−2.3, -0.7) |
| All Histologies | 1973–1978 | 2.7* (1.8, 3.6) | 1978–1989 | 0.2 (−0.1, 0.5) | 1989–2010 | −1.7* (−1.8, −1.6) | ||
| Black | ||||||||
| Small Cell | 1973–1986 | 4.1* (2.2, 6) | 1986–2010 | −3.1* (−3.8, −2.4) | ||||
| Squamous Cell | 1973–1984 | 2.0* (0.5, 3.5) | 1984–2010 | −3.8* (−4.2, −3.4) | ||||
| Large Cell | 1973–1977 | 33.5* (16.8, 52.6) | 1977–1992 | 0.2 (−1.7, 2.2) | 1992–2010 | −9.7* (−10.9, −8.5) | ||
| AC | 1973–1979 | 13.5* (8.9, 18.2) | 1979–1994 | 1.6* (0.4, 2.7) | 1994–2004 | −3.3* (−5.4, −1.1) | 2004–2010 | 2.4 (−1.7, 6.7) |
| BAC | 1973–2010 | −1.0* (−1.9, 0.1) | ||||||
| All Histologies | 1973–1986 | 2.4* (1.6, 3.2) | 1986–2010 | −2.2* (−2.5, -1.9) | ||||
*Annual percent change (APC) is significantly different from zero at α = 0.05.
APC based on incidence rates per 100,000 person-years.
AC, adenocarcinoma, BAC, bronchioloalveolar.