Table 2. Trends in lung and bronchus cancer incidence rates in the United States SEER 9 registry in females by race and histology, 1973–2010.
| Trend 1 | Trend 2 | Trend 3 | Trend 4 | Trend 5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | |
| All races | ||||||||||
| Small Cell | 1973–1982 | 9.9* (8.7, 11.1) | 1982–1991 | 3.3* (1.9, 4.6) | 1991–2010 | −1.3* (−1.7, −1) | ||||
| Squamous Cell | 1973–1981 | 6.8* (5.9, 7.7) | 1981–1988 | 3.2* (1.8, 4.5) | 1988–1999 | −0.3 (−0.9, 0.3) | 1999–2004 | −3.3* (−5.6, −0.9) | 2004–2010 | 2.4* (1.1, 3.8) |
| Large Cell | 1973–1978 | 13.7* (9.7, 17.8) | 1978–1988 | 2.7* (1.2, 4.2) | 1988–1997 | −2.8* (−4.5, −1.1) | 1997–2010 | −9.9* (−10.7, −9.2) | ||
| AC | 1973–1976 | 15.1* (10.8, 19.5) | 1976–1981 | 7.7* (5.1, 10.3) | 1981–1991 | 4.4* (3.7, 5.2) | 1991–2004 | 0.2 (−0.3, 0.6) | 2004–2010 | 3.3* (2, 4.6) |
| BAC | 1973–1976 | 16.1* (6.3, 26.7) | 1976–1989 | −1.5* (−2.5, −0.4) | 1989–1992 | 10.8 (−7, 32) | 1992–2001 | 1.9* (0, 3.9) | 2001–2010 | −1.4 (−3, 0.2) |
| All Histologies | 1973–1976 | 9.0* (6.6, 11.5) | 1976–1983 | 5.1* (4.3, 5.9) | 1983–1991 | 3.4* (2.8, 4) | 1991–2007 | 0.5* (0.3, 0.7) | 2007–2010 | −2.6* (−4.8, −0.4) |
| White | ||||||||||
| Small Cell | 1973–1982 | 10.4* (9.1, 11.7) | 1982–1991 | 3.3* (1.8, 4.8) | 1991–2010 | −1.1* (−1.5, −0.7) | ||||
| Squamous Cell | 1973–1979 | 8.5* (7, 10) | 1979–1988 | 3.6* (2.7, 4.5) | 1988–1999 | −0.1 (−0.7, 0.5) | 1999–2004 | −3.0* (−5.5, −0.5) | 2004–2010 | 3.0* (1.6, 4.4) |
| Large Cell | 1973–1978 | 14.1* (9, 19.4) | 1978–1988 | 3.0* (1.1, 4.9) | 1988–1997 | −2.6* (−4.8, −0.4) | 1997–2010 | −10.1* (−11, −9.1) | ||
| AC | 1973–1976 | 19.2* (13.8, 24.9) | 1976–1988 | 5.9* (5.3, 6.6) | 1988–1998 | 1.6*(0.7, 2.4) | 1998–2001 | −3 (−11.7, 6.4) | 2001–2010 | 2.5* (1.6, 3.4) |
| BAC | 1973–1976 | 17.5* (6.6, 29.4) | 1976–1987 | −0.8 (−2.3, 0.8) | 1987–2000 | 3.8* (2.6, 5) | 2000–2010 | −1.5* (−3, 0) | ||
| All Histologies | 1973–1976 | 10.3* (7.4, 13.3) | 1976–1988 | 4.7* (4.3, 5.1) | 1988–1997 | 1.4* (0.8, 2) | 1997–2007 | 0.3 (−0.2, 0.7) | 2007–2010 | −2.3 (−4.9, 0.4) |
| Black | ||||||||||
| Small Cell | 1973–1991 | 5.3* (3.7, 6.9) | 1991–2010 | −1.6* (−2.9, −0.2) | ||||||
| Squamous Cell | 1973–1990 | 4.6* (3.2, 6) | 1990–2010 | −1.8* (−2.8, −0.8) | ||||||
| Large Cell | 1973–1978 | 29.1* (14.6, 45.5) | 1978–1994 | 0.9 (−1.4, 3.2) | 1994–2010 | −8.4* (−10.2, −6.5) | ||||
| AC | 1973–1980 | 9.9* (7, 12.8) | 1980–1990 | 4.6* (2.7, 6.5) | 1990–2005 | 0.2 (−0.8, 1.1) | 2005–2010 | 5.9* (1.3, 10.7) | ||
| BAC | 1973–2010 | 1.6* (0.5, 2.7) | ||||||||
| All Histologies | 1973–1990 | 4.6* (4, 5.3) | 1990–2010 | 0.3 (-0.2, 0.7) | ||||||
*Annual percent change (APC) is significantly different from zero at α = 0.05.
APC is based on incidence rates per 100,000 person-years.
AC, adenocarcinoma; BAC, bronchioloalveolar.