Table 2. Fraction of the observed hetero-dimeric interfaces during five independent MD simulations of the μ-OR/δ-OR and δ-OR/κ-OR systems.
| Interface | δ-OR/κ-OR | δ-OR/μ-OR | ||
|---|---|---|---|---|
| TM1,2,H8/TM1,2,H8 | 19.10 | (6.7,36.8) | 17.70 | (4.1,33.8) |
| TM1,2/TM4,5 | 15.40 | (4.2,31.4) | 5.80 | (0.2,20.4) |
| TM1,2/TM5,6 | 15.50 | (4.4,31.1) | 17.60 | (3.9,38.4) |
| TM4,5/TM1,2 | 18.90 | (6.6,35.2) | 11.80 | (1.5,30.4) |
| TM4,5/TM5,6 | 19.40 | (7,36.5) | ― | ― |
| TM5/TM1,2 | ― | ― | 11.80 | (1.4,30.4) |
| TM5/TM5 | ― | ― | 29.30 | (10.8,52.2) |
| TM5,6/TM1,2 | 11.60 | (2.6,26.1) | 5.80 | (0.2,19.7) |
Best estimate of the fraction of each hetero-dimeric arrangement and its (2.5%,97.5%) confidence intervals (in parenthesis) are calculated as reported in the Methods section.