Table 13. Results of the feature analysis for the Kinase dataset.
| Feature | P-value | PS | Positive Median | Unlabelled Median | Feature | P-value | PS | Positive Median | Unlabelled Median |
|---|---|---|---|---|---|---|---|---|---|
| Alanine | 1.19 × 10−02 | 0.42 | 0.06 | 0.07 | Positively Charged | 3.66 × 10−03 | 0.41 | 0.14 | 0.15 |
| Arginine | 6.76 × 10−02 | 0.44 | 0.06 | 0.06 | Sequence Length | 1.21 × 10−01 | 0.55 | 682 | 587 |
| Asparagine | 3.38 × 10−03 | 0.59 | 0.04 | 0.03 | PEST Motifs | 4.16 × 10−02 | 0.44 | 0 | 0 |
| Aspartic Acid | 2.39 × 10−02 | 0.57 | 0.05 | 0.05 | Low Complexity Regions | 3.05 × 10−01 | 0.47 | 2 | 2 |
| Cysteine | 3.63 × 10−03 | 0.59 | 0.02 | 0.02 | Hydrophobicity | 4.61 × 10−02 | 0.56 | -0.35 | -0.38 |
| Glutamic Acid | 4.14 × 10−01 | 0.47 | 0.07 | 0.07 | Isoelectric Point | 4.59 × 10−03 | 0.41 | 6.87 | 7.12 |
| Glutamine | 1.32 × 10−02 | 0.42 | 0.04 | 0.04 | Signal Peptide * | 2.74 × 10−10 | 0.63 | 0 | 0 |
| Glycine | 1.67 × 10−01 | 0.54 | 0.07 | 0.06 | O-glycosylation Sites | 2.64 × 10−01 | 0.50 | 0 | 0 |
| Histidine | 4.38 × 10−01 | 0.48 | 0.03 | 0.03 | N-glycosylation Sites * | 3.84 × 10−12 | 0.64 | 0 | 0 |
| Isoleucine | 8.21 × 10−02 | 0.56 | 0.05 | 0.05 | Phosphoserine Sites | 1.78 × 10−01 | 0.54 | 2 | 1 |
| Leucine | 8.32 × 10−01 | 0.49 | 0.10 | 0.10 | Phosphothreonine Sites | 2.94 × 10−02 | 0.56 | 1 | 0 |
| Lysine | 2.25 × 10−01 | 0.46 | 0.06 | 0.06 | Phosphotyrosine Sites * | 3.49 × 10−18 | 0.74 | 2 | 0 |
| Methionine | 1.25 × 10−01 | 0.55 | 0.02 | 0.02 | Total Phosphorylation Sites * | 4.05 × 10−08 | 0.67 | 8 | 3 |
| Phenylalanine | 2.42 × 10−01 | 0.54 | 0.04 | 0.04 | Transmembrane α-helices * | 4.34 × 10−08 | 0.62 | 0 | 0 |
| Proline | 2.82 × 10−01 | 0.47 | 0.06 | 0.06 | Exposed α-helices * | 9.94 × 10−06 | 0.36 | 0.10 | 0.13 |
| Serine | 3.86 × 10−02 | 0.43 | 0.07 | 0.07 | Buried α-helices | 9.53 × 10−02 | 0.45 | 0.13 | 0.15 |
| Threonine | 6.87 × 10−02 | 0.56 | 0.05 | 0.05 | β Strands * | 5.12 × 10−10 | 0.70 | 0.17 | 0.13 |
| Tryptophan * | 7.12 × 10−05 | 0.63 | 0.01 | 0.01 | 3’ Untranslated | 2.16 × 10−01 | 0.54 | 2 | 1 |
| Tyrosine * | 3.69 × 10−04 | 0.61 | 0.03 | 0.03 | 5’ Untranslated | 2.41 × 10−01 | 0.54 | 2 | 1 |
| Valine | 8.16 × 10−02 | 0.56 | 0.06 | 0.06 | Nonsynonymous Coding | 5.29 × 10−03 | 0.59 | 24 | 17 |
| Aliphatic | 1.44 × 10−01 | 0.55 | 0.21 | 0.21 | Synonymous Coding | 4.58 × 10−01 | 0.52 | 0 | 0 |
| Aromatic | 1.83 × 10−03 | 0.60 | 0.11 | 0.10 | Binary PPIs | 1.20 × 10−02 | 0.58 | 2 | 1 |
| Charged | 6.80 × 10−02 | 0.44 | 0.26 | 0.27 | Alternative Transcripts | 2.12 × 10−01 | 0.54 | 4 | 3 |
| Negatively Charged | 6.31 × 10−01 | 0.52 | 0.12 | 0.12 | Paralogues | 9.48 × 10−01 | 0.50 | 0 | 0 |
| Non-polar | 7.77 × 10−02 | 0.56 | 0.53 | 0.53 | Body Sites Expressed In | 8.89 × 10−03 | 0.58 | 33 | 31 |
Shaded features are ones for which the PS≥0.5. The amino acid, exposed α-helix, buried α-helix and β strand features are all proportions (e.g. the Alanine feature for a protein is the number of alanine residues in the sequence divided by the sequence length), while all other features are absolute numbers.
Features with significant differences are indicated with an *.