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fMRI results from the cross-sectional analysis. Red maps represent activations during verbal fluency fMRI and blue maps represent deactivations. (A) and (B) controls; (C) and (D) other FLE patients; (E) and (F) TPM patients. The reduced area of deactivation in TPM-group (F) suggests a specific effect of topiramate on default mode network activity. fMRI, functional magnetic resonance imaging; FLE, frontal lobe epilepsy; TPM, topiramate.
