Voxel-wise group comparisons between healthy controls and patients with idiopathic generalized epilepsy using tract-based spatial statistics (TBSS). Significant increases (in red) and significant decreases (in blue) overlaid on the skeleton (in green); mean, radial, axial diffusivity (MD, D║, D┴), fractional anisotropy (FA), mean, and radial kurtosis (MK, K┴). No significant differences were observed in axial kurtosis and white-matter volume. Reproduced with permission from (15).