Table 1.

Vertebrate α2,3-Sialyltransferases-Related Sequences.

2,3-Sialyltransferase	Vertebrate Species	Accession Number	Length (AA)	% of Identities to Human Ortholog
ST3Gal I	Homo sapiens	L29555	340	100
	Mus musculus	X73523	337	81.5
	Gallus gallus	X80503	342	66.7
	Silurana tropicalis	FN550106	334	56.7
	Danio rerio	AJ864512	321	38.4
		AJ864513	330	41.4
		AM287261	317	38.6
		AM287262	317	38.9
ST3Gal II	Homo sapiens	X96667	350	100
	Mus musculus	X76989	350	93.4
	Gallus gallus	AJ585761	349	84.4
		XM_417321	313	43.0
	Silurana tropicalis	XM_002931660	351	46.5
		AJ585763	332	43.2
	Danio rerio	AJ783741	374	67.1
		AJ783740	341	43.1
ST3Gal III	Homo sapiens	L23768	375	100
	Mus musculus	X84234	374	96.5
	Gallus gallus	AJ865086	374	90.7
	Silurana tropicalis	AJ626823	358	83.2
	Danio rerio	AJ626821	356	65.6
		AJ626820	372	62.9
ST3Gal IV	Homo sapiens	L23767	333	100
	Mus musculus	X95809	333	91
	Gallus gallus	AJ866777	328	76.0
		XM_004945803	393	27.7
	Silurana tropicalis	AJ622908	330	59.5
	Danio rerio	AJ744809	329	49.9
ST3Gal V- GM3synthase	Homo sapiens	AB018356	362	100
	Mus musculus	Y15003	359	85.6
	Gallus gallus	AY515255	360	69.4
	Silurana tropicalis	FN550108	372	53.9
	Danio rerio	AJ619960	364	45.8
		AJ783742	383	28.7
ST3Gal VI	Homo sapiens	AF119391	331	100
	Mus musculus	AF119390	331	74.6
	Gallus gallus	AJ585767	329	63.4
	Silurana tropicalis	AJ626744	331	55.3

Note.—Orthologous sequences to six known human α2,3-sialyltransferase subfamilies (ST3Gal I–VI) are indicated with their accession number in GenBank, length of the deduced amino acid (AA) sequence, and percentage of identities to the human ortholog. In addition, gray background highlights other α2,3-sialyltransferase-related sequences with lower percentage of identities corresponding to new ST3Gal paralogs whose origin, evolutionary relationships, name and predicted function are to be established in this study.