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. 2015 Mar 31;5:9522. doi: 10.1038/srep09522

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Expression levels of the miRNAs were normalized to spiked-in cel-miR-39 and were calculated utilizing the 2^−ΔΔCt method. Mann-Whitney U test was used to determine statistical significance. The black dots and stars represent the outliers. The black dots: Values > Q_u + 1.5IQR; the stars: Values > Q_u + 3.0IQR. Q_u, upper quartile; IQR, inter-quartile range.