Table 1. Clinical characteristics of individuals.
| Discovery and training set | Large-scale validation set | |||
|---|---|---|---|---|
| Epilepsy | Control | Epilepsy | Control | |
| No. | 30 | 30 | 117 | 112 |
| Age, mean ± SD (y) | 26.4 ± 11.5 | 29.2 ± 5.6 | 29.8 ± 10.3 | 31.8 ± 9.0 |
| Female:Male | 15:15 | 15:15 | 57:60 | 59:53 |
| BMI, mean ± SD (kg/m2) | 22.5 ± 4.2 | 23.5 ± 3.4 | 23.0 ± 4.2 | 23.6 ± 3.3 |
| Duration, median (range) (y) | 4.5(1–32) | NA | 6(1–39) | NA |
| Seizure frequency, median(range) (/6 months) | 20(3–118) | NA | 12(1–167) | NA |
| Aetiology | ||||
| Symptomatic | 8(26.7%) | NA | 35(29.9%) | NA |
| Idiopathic | 5(16.7%) | NA | 19(16.2%) | NA |
| Crytogenic | 17(56.7%) | NA | 63(53.8%) | NA |
| Seizure type | ||||
| Partial | 12(40.0%) | NA | 39(33.3%) | NA |
| Generalized | 18(60.0%) | NA | 78(66.7%) | NA |
| AED therapy at the last clinic visit | ||||
| Monotherapy | 13(43.3%) | NA | 46(39.3%) | NA |
| Polytherapy | 17(56.7%) | NA | 71(60.7%) | NA |
Abbreviations: SD, standard deviation; BMI, body mass index; AED, antiepileptic drug; NA, not applicable.