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Schematic drawing of mechanism of signalling by ochratoxin A (OTA) aptabeacon. (a) Aptabeacon in quenched stem-loop conformation in absence of OTA; (b) Aptabeacon in unfolded conformation that allows OTA binding; (c) OTA bound to aptabeacon. Stars represent the fluorophore and the black spots the quencher. The size of the stars represents the emission intensity of the fluorophore; it increases with the distance between the fluorophore and the quencher.
