Table 3.

BRPs isolated from skin secretion of Hylidae. Peptides are aligned to compare to conventional BK. The proline residues with single underline represent the post-translational modification of hydroxyproline. The tyrosine residues with double underline represent the post-translational modification of O-sulfate.

Names	Peptide Sequences	Species
BK	RPPGFSPFR	Phasmahyla jandaia [32] Phyllomedusa azurea [30] Phyllomedusa hypochondrialis [33,34]
desArg9-BK	RPPGFSPF	Phasmahyla jandaia [32]
Hyp3-BK	RPPGFSPFR	Phyllomedusa azurea [30]
desArg9, Hyp3-BK	RPPGFSPF	Agalychnis callidryas [35]
Thr6-BK	RPPGFTPFR	Agalychnis callidryas [31,35] Pachymedusa dacnicolor [31] Phasmahyla jandaia [32] Phyllomedusa azurea [30] Phyllomedusa hypochondrialis [31,33,34]
desArg9, Thr6-BK	RPPGFTPF	Phasmahyla jandaia [32] Phyllomedusa azurea [30] Phyllomedusa hypochondrialis [31,33,34]
Hyp3, Thr6-BK	RPPGFTPFR	Agalychnis callidryas [31] Pachymedusa dacnicolor [31]
Thr6-BK-Val, Asp	RPPGFTPFRVD	Pachymedusa dacnicolor [31] Agalychnis callidryas [31]
Hyp3, Thr6-BK-Val, Asp	RPPGFTPFRVD	Agalychnis callidryas [31] Pachymedusa dacnicolor [31]
Val1, Thr6-BK	VPPGFTPFR	Phyllomedusa azurea [29,30] Phyllomedusa hypochondrialis [31,34] Phyllomedusa sauvagei [29]
Val1, Hyp2, Thr6-BK	VPPGFTPFR	Phyllomedusa azurea [30]
desArg9, Val1, Thr6-BK	VPPGFTPF	Phyllomedusa hypochondrialis [31,34]
Val1, Thr6-BK-Leu	VPPGFTPFRL	Phyllomedusa azurea [30]
Val1, Thr6-BK-Leu, Thr	VPPGFTPFRLT	Phyllomedusa azurea [30]
Glu, Pro-Val1-BK-Leu, Thr	EPVPPGFTPFRLT	Phyllomedusa azurea [30] Phyllomedusa nordestina [36]
Val1, Thr6-BK-Gln	VPPGFTPFRQ	Phyllomedusa hypochondrialis [31,34]
Val1, Thr6-BK-Gln, Ser	VPPGFTPFRQS	Phyllomedusa azurea [30] Phyllomedusa hypochondrialis [31,34]
Val1, Hyp2, Thr6-BK-Gln, Ser	VPPGFTPFRQS	Phyllomedusa azurea [37,38] Phyllomedusa hypochondrialis [31,34]
Val1, Hyp2, Thr6-BK-Gln, Thr	VPPGFTPFRQT	Phyllomedusa azurea [30]
Val1, Thr6-BK-Gln, Asp	VPPGFTPFRVD	Phyllomedusa hypochondrialis [31,34]
PK *	RPPGFSPFRIY	Phasmahyla jandaia [32] Phyllomedusa bicolor [39] Phyllomedusa hypochondrialis [33,34] Phyllomedusa rohdei [40]
Hyp3-PK *	RPPGFSPFRIY	Agalychnis callidryas [35] Phyllomedusa hypochondrialis [33,34]
Thr6-PK *	RPPGFTPFRIY	Pachymedusa dacnicolor [41,42] Phasmahyla jandaia [32] Phyllomedusa hypochondrialis [33,34] Phyllomedusa sauvagei [29]
Hyp3, Thr6-PK *	RPPGFTPFRIY	Pachymedusa dacnicolor [41,42] Phyllomedusa sauvagei [29]
Thr6, Val10-PK *	RPPGFTPFRVY	Phyllomedusa azurea [30]
Asp, Pro, Glu-Thr6, Val10-PK *	DPERPPGFTPFRVY	Phyllomedusa azurea [30]

* Both O-sulfate and non-sulfate forms of phyllokinin identified from the skin secretion in each case.