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. 2015 Mar 4;7(3):915–938. doi: 10.3390/v7030915

Figure 2.

Figure 2

Schematic representation of recombinant viruses constructed. (a) Representation of the prototypic arrangement of the HSV-1 genome with the unique long (UL) and unique short (US) regions flanked by the terminal repeat (TR) and internal repeat (IR) regions; (b) Relative genomic positions of genes mutated to create recombinant viruses; (c) Schematic representation of mutations created. Viruses lacking gM, gK, and pUL20 were constructed by replacing codons 53–55, 54–56, and 20–22 with three stop codons in the UL10, UL53, and UL20 genes, respectively.